Principal Product Development Scientist

Lead hands-on development, integration and early deployment of sample preparation and LC/LC-MS systems, from feasibility and prototypes through verification and pre-commercial deployment.
• Design and execute hypothesis-driven experiments to establish technical feasibility, resolve uncertainty, characterize system performance and guide design decisions.
• Translate customer, user and workflow needs into measurable system requirements, including functional, interface and performance requirements with appropriate acceptance criteria.
• Lead multidisciplinary system integration and troubleshooting across sample preparation, fluidics, LC/LC-MS instrumentation, mechanical and electrical hardware, software and informatics, using experimental evidence to establish root cause.
• Define system architecture, interfaces, critical parameters and integration strategies, providing technical direction and constructively challenging design assumptions through scientific and engineering evidence.
• Lead system verification and technical risk activities, including test strategy, design reviews, FMEAs, risk assessments and investigation of system performance issues.
• Own key technical documentation, including system requirements, specifications, interface definitions, test protocols, technical assessments and formal reports.
• Provide hands-on technical support at strategic customer sites, including installation, evaluation, troubleshooting and root-cause investigation of alpha, beta and pre-commercial systems, with learning fed back into system requirements and design. Approximately 40% travel may be required.

• BS, MS, or PhD in Chemistry, Physics, Engineering, or a related scientific field.

• Strong hands-on LC or LC-MS experience, with the analytical depth to assess integrated system performance.

• Experience developing instruments or integrated analytical systems, including feasibility, early development and system integration.

• Ability to translate customer and workflow needs into measurable system, functional, interface and performance requirements.

• Hands-on experience integrating and troubleshooting multidisciplinary systems spanning sample preparation, fluidics, LC/LC-MS, hardware, software and informatics.

• Demonstrated ability to investigate complex technical problems using hypothesis-driven experimentation and root-cause analysis.

• Strong technical leadership and authorship, with experience influencing cross-functional teams and producing requirements, specifications, test documentation and technical reports.

• Experience in bioprocess analytics, PAT, or biopharmaceutical applications is highly desirable.

Waters Corporation (NYSE:WAT) is a global leader in life sciences and diagnostics, dedicated to accelerating the benefits of pioneering science through analytical technologies, informatics, and service. With a focus on regulated, high-volume testing environments, our innovative portfolio harnesses deep scientific expertise across chemistry, physics, and biology. We collaborate with customers around the world to advance the release of effective, high-quality medicines, ensure the safety of food and water, and drive better patient outcomes by detecting diseases earlier, managing routine infections, and combating antibiotic resistance. Through a shared culture of relentless innovation, our passionate team of ~16,000 colleagues turn scientific challenges into breakthroughs that improve lives worldwide.

Diversity and inclusion are fundamental to our core values at Waters Corporation. It benefits our employees, our products, our customers and our community. Waters complies with all applicable federal, state, and local laws. Qualified applicants are considered without regard to sex, race, color, ancestry, national origin, citizenship status, religion, age, marital status (including civil unions), military service, veteran status, pregnancy (including childbirth and related medical conditions), genetic information, sexual orientation, gender identity, legally recognized disability, domestic violence victim status, or any other characteristic protected by law. Waters is proud to be an equal opportunity workplace and is an affirmative action employer. All hiring decisions are based solely on qualifications, merit, and business needs at the time.