Staff Research Associate - 138429

UCSD Department of Dermatology was founded in January 2015 bringing together a team of 70 faculty members specializing in Adult and Pediatric & Adolescent Dermatology, making us one of the largest Dermatology programs in the nation. Our faculty are experts in their fields and are involved in a wide range of clinical, education and research endeavors. UCSD Dermatology has an extensive basic science and clinical research portfolio that allows for substantial funding support from NIH and extramural sources. Dermatology faculties have rich programs of skin research focused on immunology, microbiology, genetics and cancer. They have funded research programs on: 1) studies on the development of the innate immune system and its interaction with the skin microbiome, 2) trials comparing alternative treatments for management of psoriasis, rosacea and atopic dermatitis biologics, 3) studies of biomarkers for acne and acne rosacea, 4) the study of genetics and epigenetics of human skin development and progression to disease, 5) atopic dermatitis inflammation and antimicrobial peptides and 6) skin cancer development and melanoma acquired drug resistance.

Under the supervision of the PI, the incumbent will perform specialized experimental techniques in Immunology, Molecular Biology, Cell Culture, and a variety of other general laboratory experiments. Duties will include handling and processing of laboratory specimens, using methods including electrophoresis, in vivo experimentation in mice using IACUC approved protocols, Western blotting, DNA and RNA extraction, immunohistochemistry, and PCR, including those involved in cell culture, clonogenic assays, kinase assays and expression of green fluorescent protein constructs. Position is also responsible for data entry and computational, and general lab duties as assigned. Operate and maintain laboratory and field instruments. Complete and maintain data properly, including lab notebooks, care and use of laboratory mice, cell lines, and bacterial strains. Perform data calculations and analysis from experimental results using appropriate computer software. Order laboratory supplies and handle biohazardous materials. Inventory and dispose of biohazardous wastes.

• Theoretical knowledge of a life science such as is typically acquired by a Bachelor's Degree. Related fields may include any of the following fields of study: molecular biology and biochemistry.

• Effective and diplomatic oral and written communication and interpersonal skills. Ability to work with a diverse group.

• Willingness to learn new techniques and tasks and share knowledge to inform and teach students and paraprofessionals new techniques.

• Demonstrated ability to read, interpret and apply protocols in conducting research. Demonstrated ability in following step wise experimental protocols. Skill to troubleshoot adaptations of experimental protocols.

• Enthusiasm for learning and a genuine interest in scientific research. Willingness and ability to learn new skills, research methods, and scientific principles.

• Demonstrated ability to follow established Safety and Biohazardous Material Guidelines.

• Manual dexterity and legible handwriting. Ability to assist with general lab maintenance, including cleaning and restocking supplies in the lab.

• Knowledge of biosafety techniques and practices. Experience to work with chemical and biological hazards and to recognize safety problems.

• Good organizational and effective time management skills.

• Experience with the operation of a personal computer and software application, such as Access, MS Word and Excel. Willingness and ability to learn new software for analysis.

• Demonstrated experience in Dermatologic research and work with live animals such as mice.

• Demonstrated knowledge to read and use Material Safety Data Sheet's. Knowledge of UCSD Environmental Health and Safety requirements and the ability to write with correct syntax and grammar and to clearly communicate ideas and protocols in writing to EH&S. Experienced in working and maintaining a sterile environment.

• Demonstrated experience with DNA extraction from skin swabs.

• Demonstrated experience with electrophoresis, Western blotting, DNA and RNA extraction, immunohistochemistry, PCR, including those involved in cell culture, clonogenic assays, kinase assays, tape strip analysis, protein and protease assays and ELISA analysis.

• Demonstrated skill in the operation and maintenance of various lab equipment such as used in DNA and protein analysis.

• Strong communication skills (both verbal and written) needed to interact professionally and effectively in the work environment, as well as effectively and accurately document research procedures. Ability to read, comprehend and discuss research materials.

• Demonstrated skill in accurate record keeping and ability to organize, analyze, and calculate data.

• Employment is subject to a criminal background check.

If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements.

If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable.

UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team!

Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached.

To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community.

The University of California is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected status under state or federal law.

For the University of California's Anti-Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination

UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information.

UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening.

Misconduct Disclosure Requirement: As a condition of employment, the final candidate who accepts an offer of employment will be required to disclose if they have been subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct; or have filed an appeal of a finding of substantiated misconduct with a previous employer.

a. "Misconduct" means any violation of the policies governing employee conduct at the applicant's previous place of employment, including, but not limited to, violations of policies prohibiting sexual harassment, sexual assault, or other forms of harassment, or discrimination, as defined by the employer. For reference, below are UC's policies addressing some forms of misconduct:

• UC Sexual Violence and Sexual Harassment Policy
• UC Anti-Discrimination Policy
• Abusive Conduct in the Workplace