Sr. Research Associate, Single Cell Assay Productization (Contract) (P-4977)

We are seeking a Senior Research Associate to join the Assay Productization team to support the development and commercial launch of new Single Cell Genomic products on a six months contract basis, with the potential to extend. Assay Productization acts as the interface between R&D and Production. The team is involved in all stages of product development from concept to post-launch activities. This is a unique cross-disciplinary position that will work closely with a variety of groups including Molecular Biology, Chemistry, Microfluidics, QC, and Manufacturing, to develop and validate novel reagents for the rapid expansion of 10x product lines. Candidates must have a broad working knowledge of molecular biology and be able to apply that knowledge creatively and independently in a fast-paced work environment. Research experience with DNA oligos, antibody assays, RNA assays, and next generation sequencing (NGS) is desired. Experience in new product introduction and manufacturing operations is a big plus.This role requires a candidate who can be relied upon to produce consistent, high-quality data without needing daily tasks assigned.

What You Will Be Doing:

• Create NGS libraries from single cells, tissues, or isolated DNA/RNA using 10x instruments and consumables.
• Preparation, formulation, and testing of newly designed 10x reagents either from SOPs or R&D protocols.
• Assist with reagent guard banding and stability studies.
• Assist with new QC method development and implementation to assess reagent quality through a variety of analytical and functional tests.
• Perform troubleshooting analysis of failed experiments and reagent issues as they arise in the product line.
• Facilitate successful handoffs from R&D to Operations by training QC and Production staff on new workflows or methods.
• Present your own work to internal stakeholders, providing clear explanations of methodology and data interpretation.

Minimum Qualifications:

• BS or MS in molecular biology, biochemistry, genetics, analytical chemistry, or related fields.
• 3+ years (BS) or 2+ years (MS) of experience in reagent or assay development, preferably within the Biotech industry.
• Deep understanding of molecular biology and hands-on experience with NGS library generation and data evaluation.
• Mastery of analytical techniques including qPCR, nucleic acid isolation, and use of Bioanalyzers or real-time PCR instruments.
• Ability to perform complex multi-step experiments with detailed and diligent attention to planning, organization, hands-on technique, and record keeping.
• Experience troubleshooting molecular biology-based assays.
• Strong collaboration and communication skills.
• Desire to work in a flexible and fast-paced startup environment.

Preferred Qualifications:

• Previous work with a variety of NGS sample preparation workflows and analysis. Strong preference for single cell and/or RNA-Seq workflows.
• Past work in a process or product development role, especially technology transfer to manufacturing and/or QC groups.
• Experience working with new and untested reagents.
• Experience creating and optimizing novel assays.